When Cells Become Drugs: The Rise of Allogeneic CAR-T
CAR-T therapy introduced a radical idea: using living cells as medicine. Now, scientists are developing allogeneic CAR-T—an off-the-shelf version that could make cell therapy faster, more accessible, and more scalable. Discover how engineered immune cells are transforming cancer treatment and paving the way for a new generation of living medicines.
cssDNA as the Next Frontier in Genetic Medicine
Circular single-stranded DNA (cssDNA) is emerging as a powerful new modality in genetic medicine. Once limited by manufacturing challenges, advances in enzymatic production have unlocked its potential as a stable, programmable, and potentially less immunogenic platform for gene replacement and cell engineering. From precise CRISPR donor templates to in vivo immune programming, cssDNA may help complete the genetic medicine toolkit — shifting the field from simply editing genes to installing new biological instructions with intention.