A Look at Virtual Cells—and How They Could Change Experimental Cell Biology
What if we could explore hundreds of cellular perturbations before choosing which experiments to run at the bench? AIDO Cell offers an early look at what virtual cells could bring to experimental biology—from simulating complex cellular responses to helping scientists prioritize which hypotheses are worth testing in the real world.
When Cells Become Drugs: The Rise of Allogeneic CAR-T
CAR-T therapy introduced a radical idea: using living cells as medicine. Now, scientists are developing allogeneic CAR-T—an off-the-shelf version that could make cell therapy faster, more accessible, and more scalable. Discover how engineered immune cells are transforming cancer treatment and paving the way for a new generation of living medicines.
cssDNA as the Next Frontier in Genetic Medicine
Circular single-stranded DNA (cssDNA) is emerging as a powerful new modality in genetic medicine. Once limited by manufacturing challenges, advances in enzymatic production have unlocked its potential as a stable, programmable, and potentially less immunogenic platform for gene replacement and cell engineering. From precise CRISPR donor templates to in vivo immune programming, cssDNA may help complete the genetic medicine toolkit — shifting the field from simply editing genes to installing new biological instructions with intention.
Beyond the Cage: How the FDA Modernization Act is Accelerating the Shift Toward Human-Based Models
The FDA Modernization Act 2.0 has opened the door to a new era in preclinical research — one powered by organoids, organs-on-chips, iPSC systems, ex vivo human tissues, and AI-driven prediction tools. As regulators push for human-relevant science, these technologies are reshaping how drugs are designed, tested, and brought to patients. This article explores how and why the shift is accelerating.
The Superbug Wars
Antibiotic resistance is fueling a dangerous rise in “superbugs” that evade modern medicine. From MRSA to Candida auris, resistant pathogens are spreading worldwide. But new solutions are emerging—like phage therapy, antimicrobial peptides, and far-UVC light—that may give us a fighting chance in the battle against antimicrobial resistance.
Undruggable No More
For decades, “undruggable” proteins were considered off-limits to drug discovery. Today, new approaches—from PROTACs and covalent inhibitors to AI-guided design—are redefining what’s possible, turning once impossible targets into breakthroughs for patients.
Unleashing the Future of Therapeutics: Antibody Discovery
Antibodies are no longer just immune system defenders—they're precision tools reshaping the treatment of cancer, autoimmune diseases, infections, and more. In this article, we dive into how therapeutic antibodies are discovered, engineered, and fast-tracked into life-saving medicines.
The Living Lab Bench: The Role of 3D Bioprinting in Smarter Drug Development
What if we could print living tissue—tiny hearts, slivers of brain, even organ systems—right in the lab? 3D bioprinting is revolutionizing drug development, personalized medicine, and regenerative therapies. Explore how this groundbreaking tech is reshaping the future of biology, one printed layer at a time.
Inside the Cell: How Cell-Based Assays Reveal Drug Function
How do scientists know if a drug is working inside cells? From glowing proteins to cell survival tests, this article unpacks the powerful assays that reveal a drug’s true behavior—right where it matters most.
Engineering Protein Localization
A New Approach for Treating Protein Mislocalization Disorders
The Promise of In-Womb Treatment: A New Frontier in Treating Genetic Disorders Before Birth
A new era in fetal medicine